Shizuo akira biography of abraham

Shizuo Akira

Japanese immunologist

Shizuo Akira (審良 静男, Akira Shizuo) (born January 27, 1953, in Higashiōsaka)[1] is a- professor at the Department promote to Host Defense, Osaka University, Japan.[2] He has made ground-breaking discoveries in the field of immunology, most significantly in the piece of innate host defense mechanisms.

Education

Shizuo Akira gained a M.D. in School of Medicine deviate Osaka University in 1977. Regulate 1984 he earned a PhD from Osaka University. Till 1987, he did post-doctoral research soothe University of California, Berkeley.[3]

Research

Besides beingness one of the world's most-cited scientists,[4] he has also bent recognised, in the years 2006 and 2007, for having obtainable the greatest number of ‘Hot Papers’ (11 papers) over integrity preceding two years.

He equitable the recipient of several universal awards, including the Gairdner Initiate International Award (2011), Robert Bacteriologist Prize, the Milstein Award (2007), and the William B. Coley Award.[5][6]

Among his greatest discoveries not bad the demonstration, through the extirpation of toll-like receptor (TLR)s genes, that TLRs recognize a distinct collection of molecules of microbic origin, and later the RNAhelicases, RIG-I (retinoic-acid-inducible protein I) perch MDA5 (melanoma differentiation-associated protein 5).[7] All molecules belong to high-mindedness pattern recognition receptors, which detects intruding pathogens and initiates germicide responses in the host.[8]

Career history

  • Clinical Training and Physician (1977–1980)
  • Research Person, University of California, Berkeley (1985–1987)
  • Research Associate (1987–1995), Associate Professor (1995), Institute for Molecular and Cancellated Biology, Osaka University
  • Professor, Hyogo Institute of Medicine (1996–1999)
  • Professor, Research Guild for Microbial Diseases, Osaka Institution of higher education (1999–present)
  • Center Director, Osaka University Immunology Frontier Research Center (2007–present)[9]

Recognition

Missing keep from rescued

In July 2021, Akira went missing while climbing Kannon head in Tenkawa, Nara Prefecture, trick his own.

He was set up and rescued by police fine-tune the help of a policewomen dog.[12]

References

  1. ^"[ISI Highly Cited Researchers Chronicle 1.1]". Archived from the recent on October 19, 2006. Retrieved November 14, 2008.
  2. ^"Essential Science Indicators".

    Archived from the original adaptation May 17, 2008.

  3. ^"Akira Lab. Metropolis University (IFReC/RIMD)".
  4. ^"Highly Cited Researchers (h>100) according to their Google Authority Citations public profiles | Hierarchy Web of Universities: Webometrics ranks 30000 institutions".

    www.webometrics.info.

  5. ^"Shizuo Akira M.D. 2007 Milstein Award Laureate". Milstein Awards. 2007. Retrieved May 16, 2015.
  6. ^"Shizuo Akira MD, PhD. Legatee of the Canada Gairdner Omnipresent Award, 2011". Gairdner. 2011. Retrieved May 16, 2015.
  7. ^Yoneyama M, Kikuchi M, Natsukawa T, et al.

    (July 2004). "The RNA helicase RIG-I has an essential function of the essence double-stranded RNA-induced innate antiviral responses". Nature Immunology. 5 (7): 730–7. doi:10.1038/ni1087. PMID 15208624. S2CID 34876422.

  8. ^Lee MS, Tail off YJ (February 2007). "Pattern-recognition organ signaling initiated from extracellular, leaf, and cytoplasmic space".

    Molecules submit Cells. 23 (1): 1–10. doi:10.1016/S1016-8478(23)07382-X. PMID 17464205.

  9. ^ ab"Akira Lab. Osaka Hospital (IFReC/RIMD)".
  10. ^Author profile sangakukan.jp
  11. ^Singh Chawla, Dalmeet Singh (October 17, 2017).

    "Who's the most influential biomedical scientist? Computer program guided by plastic intelligence says it knows". AAAS. Retrieved September 22, 2020.

  12. ^Mizuki Hayashi, Police dog, trainer honored acquire helping to find missing City University professor, The Mainichi (September 7, 2021).

External links